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Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes

BACKGROUND AND AIMS: Spinal anesthesia is a technique widely used for gynecological, lower abdominal, pelvic and lower limb procedures. Even though it causes a profound nerve block, it is associated with profound hypotension. AIMS OF THE STUDY: To assess the effect of the speed of injection of heavy...

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Autores principales: Jacob, Ann Riya, Paul, Jerry, Rajan, Sunil, Ravindran, Greeshma C., Kumar, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004274/
https://www.ncbi.nlm.nih.gov/pubmed/35422549
http://dx.doi.org/10.4103/aer.aer_1_22
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author Jacob, Ann Riya
Paul, Jerry
Rajan, Sunil
Ravindran, Greeshma C.
Kumar, Lakshmi
author_facet Jacob, Ann Riya
Paul, Jerry
Rajan, Sunil
Ravindran, Greeshma C.
Kumar, Lakshmi
author_sort Jacob, Ann Riya
collection PubMed
description BACKGROUND AND AIMS: Spinal anesthesia is a technique widely used for gynecological, lower abdominal, pelvic and lower limb procedures. Even though it causes a profound nerve block, it is associated with profound hypotension. AIMS OF THE STUDY: To assess the effect of the speed of injection of heavy bupivacaine on quality of block and hemodynamic changes in patients undergoing gynecological surgeries under spinal anesthesia. METHODS: This was a prospective randomized study conducted on 40 patients. Group F patients were given 3.2 mL of 0.5% heavy bupivacaine intrathecally in 15 s and Group S patients were given the same drug over 60 s. The time to achieve T(10) dermatomal block, maximum block height, block height at 5 min were recorded. Heart rate (HR), systolic, diastolic blood pressures, and mean arterial pressures (MAP) were also recorded at different time points. RESULTS: HR, systolic BP, diastolic BP, and MAPs and mean block height at 5 min were comparable between the two groups at all time points. The time to achieve T(10) dermatome block was significantly faster in Group F (1.85 ± 1.14 min) as compared to Group S (3.98 ± 1.58 min). Majority of patients in Group F (65%) had a maximum block up to T(6) and those in Group S (45%) had a block upto T(4). The usage of vasopressors was found to be significantly higher in Group F compared to Group S with P = 0.041. CONCLUSION: Using faster speed of injection of heavy bupivacaine during spinal anesthesia can lead to faster achievement of blockade but with significantly higher usage of vasopressors.
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spelling pubmed-90042742022-04-13 Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes Jacob, Ann Riya Paul, Jerry Rajan, Sunil Ravindran, Greeshma C. Kumar, Lakshmi Anesth Essays Res Original Article BACKGROUND AND AIMS: Spinal anesthesia is a technique widely used for gynecological, lower abdominal, pelvic and lower limb procedures. Even though it causes a profound nerve block, it is associated with profound hypotension. AIMS OF THE STUDY: To assess the effect of the speed of injection of heavy bupivacaine on quality of block and hemodynamic changes in patients undergoing gynecological surgeries under spinal anesthesia. METHODS: This was a prospective randomized study conducted on 40 patients. Group F patients were given 3.2 mL of 0.5% heavy bupivacaine intrathecally in 15 s and Group S patients were given the same drug over 60 s. The time to achieve T(10) dermatomal block, maximum block height, block height at 5 min were recorded. Heart rate (HR), systolic, diastolic blood pressures, and mean arterial pressures (MAP) were also recorded at different time points. RESULTS: HR, systolic BP, diastolic BP, and MAPs and mean block height at 5 min were comparable between the two groups at all time points. The time to achieve T(10) dermatome block was significantly faster in Group F (1.85 ± 1.14 min) as compared to Group S (3.98 ± 1.58 min). Majority of patients in Group F (65%) had a maximum block up to T(6) and those in Group S (45%) had a block upto T(4). The usage of vasopressors was found to be significantly higher in Group F compared to Group S with P = 0.041. CONCLUSION: Using faster speed of injection of heavy bupivacaine during spinal anesthesia can lead to faster achievement of blockade but with significantly higher usage of vasopressors. Wolters Kluwer - Medknow 2021 2022-03-01 /pmc/articles/PMC9004274/ /pubmed/35422549 http://dx.doi.org/10.4103/aer.aer_1_22 Text en Copyright: © 2022 Anesthesia: Essays and Researches https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Jacob, Ann Riya
Paul, Jerry
Rajan, Sunil
Ravindran, Greeshma C.
Kumar, Lakshmi
Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes
title Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes
title_full Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes
title_fullStr Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes
title_full_unstemmed Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes
title_short Effect of Injection Speed of Heavy Bupivacaine in Spinal Anesthesia on Quality of Block and Hemodynamic Changes
title_sort effect of injection speed of heavy bupivacaine in spinal anesthesia on quality of block and hemodynamic changes
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004274/
https://www.ncbi.nlm.nih.gov/pubmed/35422549
http://dx.doi.org/10.4103/aer.aer_1_22
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