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Local anesthetic levobupivacaine inhibits stemness of osteosarcoma cells by epigenetically repressing MAFB though reducing KAT5 expression

Osteosarcoma is the most prevalent bone cancer and accounts for over half of sarcomas. In this study, we identified that the treatment of levobupivacaine suppressed proliferation of osteosarcoma cells in vitro. The tumor xenograft analysis showed that levobupivacaine significantly repressed the oste...

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Detalles Bibliográficos
Autores principales: Wang, Zhan, Song, Yuxin, Zhang, Hui, Yang, Yang, Zhang, Suifeng, Wang, Wenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004559/
https://www.ncbi.nlm.nih.gov/pubmed/35333774
http://dx.doi.org/10.18632/aging.203975

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