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Local anesthetic levobupivacaine inhibits stemness of osteosarcoma cells by epigenetically repressing MAFB though reducing KAT5 expression
Osteosarcoma is the most prevalent bone cancer and accounts for over half of sarcomas. In this study, we identified that the treatment of levobupivacaine suppressed proliferation of osteosarcoma cells in vitro. The tumor xenograft analysis showed that levobupivacaine significantly repressed the oste...
Autores principales: | Wang, Zhan, Song, Yuxin, Zhang, Hui, Yang, Yang, Zhang, Suifeng, Wang, Wenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004559/ https://www.ncbi.nlm.nih.gov/pubmed/35333774 http://dx.doi.org/10.18632/aging.203975 |
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