SPOROS: A pipeline to analyze DISE/6mer seed toxicity

microRNAs (miRNAs) are (18-22nt long) noncoding short (s)RNAs that suppress gene expression by targeting the 3’ untranslated region of target mRNAs. This occurs through the seed sequence located in position 2-7/8 of the miRNA guide strand, once it is loaded into the RNA induced silencing complex (RI...

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Detalles Bibliográficos
Autores principales: Bartom, Elizabeth T., Kocherginsky, Masha, Paudel, Bidur, Vaidyanathan, Aparajitha, Haluck-Kangas, Ashley, Patel, Monal, O’Shea, Kaitlyn L., Murmann, Andrea E., Peter, Marcus E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004739/
https://www.ncbi.nlm.nih.gov/pubmed/35358200
http://dx.doi.org/10.1371/journal.pcbi.1010022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004739/
https://www.ncbi.nlm.nih.gov/pubmed/35358200
http://dx.doi.org/10.1371/journal.pcbi.1010022

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