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SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen

The SIRPα-CD47 axis plays an important role in T cell recruitment to sites of immune reaction and inflammation but its role in T cell antigen priming is incompletely understood. Employing OTII TCR transgenic mice bred to Cd47-/- (Cd47KO) or SKI mice, a knock-in transgenic animal expressing non-signa...

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Detalles Bibliográficos
Autores principales:	Autio, Anu, Wang, Huan, Velázquez, Francisco, Newton, Gail, Parkos, Charles A., Engel, Pablo, Engelbertsen, Daniel, Lichtman, Andrew H., Luscinskas, Francis W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004769/ https://www.ncbi.nlm.nih.gov/pubmed/35413056 http://dx.doi.org/10.1371/journal.pone.0266566

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