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Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real

OBJECTIVES: Kidney disease is one of the microvascular complications of diabetes mellitus (DM) with little research and a strong association with cardiovascular disease (CVD). The objective of this study is to characterize the prevalence of kidney disease in a population of patients with type 2 diab...

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Autores principales: Salmeri, Emiliano, Elbert, Alicia, Lavalle-Cobo, Augusto, Aranguren, Florencia, Sanabria, Hugo, Giorgi, Mariano, Forte, Ezequiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Permanyer Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005173/
https://www.ncbi.nlm.nih.gov/pubmed/34260578
http://dx.doi.org/10.24875/ACM.20000566
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author Salmeri, Emiliano
Elbert, Alicia
Lavalle-Cobo, Augusto
Aranguren, Florencia
Sanabria, Hugo
Giorgi, Mariano
Forte, Ezequiel
author_facet Salmeri, Emiliano
Elbert, Alicia
Lavalle-Cobo, Augusto
Aranguren, Florencia
Sanabria, Hugo
Giorgi, Mariano
Forte, Ezequiel
author_sort Salmeri, Emiliano
collection PubMed
description OBJECTIVES: Kidney disease is one of the microvascular complications of diabetes mellitus (DM) with little research and a strong association with cardiovascular disease (CVD). The objective of this study is to characterize the prevalence of kidney disease in a population of patients with type 2 diabetes who attend outpatient control by cardiology, to evaluate its degree of investigation and whether its presence impacts on the achievement of therapeutic goals and use of antidiabetics with cardiovascular and kidney protective effect. METHODS: Cross-sectional, observational and multicenter study, carried out in 44 centers in Argentina between May and July 2019. RESULTS: A population with 693 patients with DM was included. The prevalence of CVD was 47.5% (329 patients) and that of microvascular disease was 42.3%. Albuminuria was evaluated only in 46.2% of the patients and was significantly higher in the group with renal impairment (RI). The presence of CVD in patients with RI was greater than in those without RI (64.8% vs. 42.2%; p = 0.0001). The presence of albuminuria was associated with a higher prevalence of CVD. The achievement of therapeutic goals was scarce and no differences were evidenced based on the presence of RI, except for the LDL goal. Low prescription of antidiabetic drugs with proven cardiovascular and kidney benefit was observed. CONCLUSIONS: This study highlights the importance of the active search for kidney disease in patients with DM, exposing the low scope of therapeutic goals and the prescription of antidiabetic drugs with cardiovascular and kidney benefit.
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spelling pubmed-90051732022-04-15 Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real Salmeri, Emiliano Elbert, Alicia Lavalle-Cobo, Augusto Aranguren, Florencia Sanabria, Hugo Giorgi, Mariano Forte, Ezequiel Arch Cardiol Mex Artículo De Investigación OBJECTIVES: Kidney disease is one of the microvascular complications of diabetes mellitus (DM) with little research and a strong association with cardiovascular disease (CVD). The objective of this study is to characterize the prevalence of kidney disease in a population of patients with type 2 diabetes who attend outpatient control by cardiology, to evaluate its degree of investigation and whether its presence impacts on the achievement of therapeutic goals and use of antidiabetics with cardiovascular and kidney protective effect. METHODS: Cross-sectional, observational and multicenter study, carried out in 44 centers in Argentina between May and July 2019. RESULTS: A population with 693 patients with DM was included. The prevalence of CVD was 47.5% (329 patients) and that of microvascular disease was 42.3%. Albuminuria was evaluated only in 46.2% of the patients and was significantly higher in the group with renal impairment (RI). The presence of CVD in patients with RI was greater than in those without RI (64.8% vs. 42.2%; p = 0.0001). The presence of albuminuria was associated with a higher prevalence of CVD. The achievement of therapeutic goals was scarce and no differences were evidenced based on the presence of RI, except for the LDL goal. Low prescription of antidiabetic drugs with proven cardiovascular and kidney benefit was observed. CONCLUSIONS: This study highlights the importance of the active search for kidney disease in patients with DM, exposing the low scope of therapeutic goals and the prescription of antidiabetic drugs with cardiovascular and kidney benefit. Permanyer Publications 2022 2021-07-14 /pmc/articles/PMC9005173/ /pubmed/34260578 http://dx.doi.org/10.24875/ACM.20000566 Text en Copyright: © 2022 Permanyer https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Artículo De Investigación
Salmeri, Emiliano
Elbert, Alicia
Lavalle-Cobo, Augusto
Aranguren, Florencia
Sanabria, Hugo
Giorgi, Mariano
Forte, Ezequiel
Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real
title Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real
title_full Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real
title_fullStr Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real
title_full_unstemmed Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real
title_short Relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real
title_sort relación entre enfermedad cardiovascular y renal en una muestra de pacientes con diabetes del mundo real
topic Artículo De Investigación
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005173/
https://www.ncbi.nlm.nih.gov/pubmed/34260578
http://dx.doi.org/10.24875/ACM.20000566
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