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A conditional gene-based association framework integrating isoform-level eQTL data reveals new susceptibility genes for schizophrenia
Linkage disequilibrium and disease-associated variants in the non-coding regions make it difficult to distinguish the truly associated genes from the redundantly associated genes for complex diseases. In this study, we proposed a new conditional gene-based framework called eDESE that leveraged an im...
Autores principales: | Li, Xiangyi, Jiang, Lin, Xue, Chao, Li, Mulin Jun, Li, Miaoxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005191/ https://www.ncbi.nlm.nih.gov/pubmed/35412455 http://dx.doi.org/10.7554/eLife.70779 |
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