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Choline Protects the Heart from Doxorubicin-Induced Cardiotoxicity through Vagal Activation and Nrf2/HO-1 Pathway
Choline is a precursor of the major neurotransmitter acetylcholine and has been demonstrated beneficial in diverse models of cardiovascular disease. Here, we sought to verify that choline protects the heart from DOX-induced cardiotoxicity and the underlying mechanisms. The results showed that DOX tr...
Autores principales: | Guo, Fuding, Wang, Yueyi, Wang, Jun, Liu, Zhihao, Lai, Yanqiu, Zhou, Zhen, Liu, Zihan, Zhou, Yuyang, Xu, Xiao, Li, Zeyan, Wang, Meng, Yu, Fu, Hu, Ruijie, Zhou, Liping, Jiang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005275/ https://www.ncbi.nlm.nih.gov/pubmed/35422894 http://dx.doi.org/10.1155/2022/4740931 |
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