The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor

Complement activation on cell surfaces leads to the massive deposition of C3b, iC3b, and C3dg, the main complement opsonins. Recognition of iC3b by complement receptor type 3 (CR3) fosters pathogen opsonophagocytosis by macrophages and the stimulation of adaptive immunity by complement-opsonized ant...

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Detalles Bibliográficos
Autores principales: Fernández, Francisco J., Santos-López, Jorge, Martínez-Barricarte, Rubén, Querol-García, Javier, Martín-Merinero, Héctor, Navas-Yuste, Sergio, Savko, Martin, Shepard, William E., Rodríguez de Córdoba, Santiago, Vega, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005620/
https://www.ncbi.nlm.nih.gov/pubmed/35413960
http://dx.doi.org/10.1038/s41467-022-29580-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005620/
https://www.ncbi.nlm.nih.gov/pubmed/35413960
http://dx.doi.org/10.1038/s41467-022-29580-2

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