Cargando…

The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor

Complement activation on cell surfaces leads to the massive deposition of C3b, iC3b, and C3dg, the main complement opsonins. Recognition of iC3b by complement receptor type 3 (CR3) fosters pathogen opsonophagocytosis by macrophages and the stimulation of adaptive immunity by complement-opsonized ant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernández, Francisco J., Santos-López, Jorge, Martínez-Barricarte, Rubén, Querol-García, Javier, Martín-Merinero, Héctor, Navas-Yuste, Sergio, Savko, Martin, Shepard, William E., Rodríguez de Córdoba, Santiago, Vega, M. Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005620/ https://www.ncbi.nlm.nih.gov/pubmed/35413960 http://dx.doi.org/10.1038/s41467-022-29580-2

Ejemplares similares

C3b/iC3b Deposition on Streptococcus pneumoniae Is Not Affected by HIV Infection
por: Hyams, Catherine, et al.
Publicado: (2010)

Moieties of Complement iC3b Recognized by the I-domain of Integrin αXβ2
por: Choi, Jeongsuk, et al.
Publicado: (2020)

Deposition of C3b and iC3b onto particulate activators of the human complement system. Quantitation with monoclonal antibodies to human C3
Publicado: (1985)

Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase
por: Paixão-Cavalcante, Danielle, et al.
Publicado: (2009)

Association of Blood Concentrations of Complement Split Product iC3b and Serum C3 With Systemic Lupus Erythematosus Disease Activity
por: Kim, Alfred H. J., et al.
Publicado: (2019)

Sequential Increase in Complement Factor I, iC3b, and Cells Expressing CD11b or CD14 in Cutaneous Vasculitis
por: Rahkola, Dina, et al.
Publicado: (2022)

The Response of Tissue Mast Cells to TLR3 Ligand Poly(I:C) Treatment
por: Witczak, Piotr, et al.
Publicado: (2020)

Increase in complement iC3b is associated with anti-inflammatory cytokine expression during late pregnancy in mice
por: Nakamura, Keigo, et al.
Publicado: (2017)

Immunotherapeutic effects of intratumoral nanoplexed poly I:C
por: Aznar, M. Angela, et al.
Publicado: (2019)

Experimental ion mobility measurements in pure iC$_4$H$_{10}$10 and Ar-iC$_4$H$_{10}$ mixtures
por: Cortez, A F V, et al.
Publicado: (2019)

ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells
por: Laura, Gemma, et al.
Publicado: (2021)

Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the Chikungunya virus in BEAS-2B cells
por: Li, Yong-Gang, et al.
Publicado: (2012)

Poly I:C enhances cycloheximide-induced apoptosis of tumor cells through TLR3 pathway
por: Jiang, Qun, et al.
Publicado: (2008)

Clozapine Prevents Poly (I:C) Induced Inflammation by Modulating NLRP3 Pathway in Microglial Cells
por: V. Giridharan, Vijayasree, et al.
Publicado: (2020)

Exploiting poly(I:C) to induce cancer cell apoptosis
por: Bianchi, Francesca, et al.
Publicado: (2017)

Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice
por: Stowell, Nicole C, et al.
Publicado: (2009)

Ioh. Angelij Werdenhagen I.C. De rebuspublicis, Hanseaticis : Tractatus generalis
por: Werdenhagen, Johann angelius von, 1581-1652
Publicado: (1631)

Control of Interferon Production in Rabbit Cells Treated with Poly I:C
por: Armstrong, John A.
Publicado: (1970)

Pathological Role of Interleukin-17 in Poly I:C-Induced Hepatitis
por: He, Jianqin, et al.
Publicado: (2013)

Towards a Mechanism for Poly(I·C) Antiviral Priming in Oysters
por: Martins, Nelson E.
Publicado: (2020)

Human papillomavirus-exposed Langerhans cells are activated by stabilized Poly-I:C
por: Da Silva, Diane M., et al.
Publicado: (2015)

I.C.S. reference library : a series of textbooks prepared for the students of the International Correspondence Schools, and containing in permanent form the instruction papers, examination questions, and keys used in their various courses ...
Publicado: (1904)

Expressional induction of Paralichthys olivaceus cathepsin B gene in response to virus, poly I:C and lipopolysaccharide()
por: Zhang, Fu-Tie, et al.
Publicado: (2008)

Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells
por: McCartney, Stephen, et al.
Publicado: (2009)

TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles
por: Frank-Bertoncelj, Mojca, et al.
Publicado: (2018)

TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand
por: Lim, Chan Seok, et al.
Publicado: (2022)

Two conformational forms of target-bound iC3b that distinctively bind complement receptors 1 and 2 and two specific monoclonal antibodies
por: Nilsson, Ulf R., et al.
Publicado: (2011)

Combination of poly I:C and Pam3CSK4 enhances activation of B cells in vitro and boosts antibody responses to protein vaccines in vivo
por: Weir, Genevieve M., et al.
Publicado: (2017)

CircRNA-9119 suppresses poly I:C induced inflammation in Leydig and Sertoli cells via TLR3 and RIG-I signal pathways
por: Qin, Le, et al.
Publicado: (2019)

Instrument Control (iC) – An Open-Source Software to Automate Test Equipment
por: Pernstich, K. P.
Publicado: (2012)

Combined Adjuvant of Poly I:C Improves Antitumor Effects of CAR-T Cells
por: Di, Shengmeng, et al.
Publicado: (2019)

Sex differences and similarities in the neuroimmune response to central administration of poly I:C
por: Posillico, Caitlin K., et al.
Publicado: (2021)

Mouse primary microglia respond differently to LPS and poly(I:C) in vitro
por: He, Yingbo, et al.
Publicado: (2021)

Immune System Modulation by the Adjuvants Poly (I:C) and Montanide ISA 720
por: Marques, Rodolfo F., et al.
Publicado: (2022)

Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C in mice
por: Cui, Jian, et al.
Publicado: (2020)

Switchable Interlayer Magnetic Coupling of Bilayer CrI(3)
por: Jiang, Yue, et al.
Publicado: (2021)

Low energy electrodynamics of CrI(3) layered ferromagnet
por: Tomarchio, Luca, et al.
Publicado: (2021)

Phonon Anharmonicity and Spin–Phonon Coupling in CrI(3)
por: Tomarchio, Luca, et al.
Publicado: (2023)

Emotional Contagion is not Altered in Mice Prenatally Exposed to Poly (I:C) on Gestational Day 9
por: Gonzalez-Liencres, Cristina, et al.
Publicado: (2016)

Induction of alopecia areata in C3H/HeJ mice using polyinosinic-polycytidylic acid (poly[I:C]) and interferon-gamma
por: Shin, Jung-Min, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a8ejd9uujs3p5bshr9d9kpp58d