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Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Genetics play an important role in late-onset Alzheimer’s Disease (AD) etiology and dozens of genetic variants have been implicated in AD risk through large-scale GWAS meta-analyses. However, the precise mechanistic effects of most of these variants have yet to be determined. Deeply phenotyped cohor...

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Detalles Bibliográficos
Autores principales:	Heath, Laura, Earls, John C., Magis, Andrew T., Kornilov, Sergey A., Lovejoy, Jennifer C., Funk, Cory C., Rappaport, Noa, Logsdon, Benjamin A., Mangravite, Lara M., Kunkle, Brian W., Martin, Eden R., Naj, Adam C., Ertekin-Taner, Nilüfer, Golde, Todd E., Hood, Leroy, Price, Nathan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005657/ https://www.ncbi.nlm.nih.gov/pubmed/35413975 http://dx.doi.org/10.1038/s41598-022-09825-2

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