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Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy
We report a 54‐year‐old man with treatment‐resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005678/ https://www.ncbi.nlm.nih.gov/pubmed/35432999 http://dx.doi.org/10.1002/ccr3.5651 |
| _version_ | 1784686508823805952 |
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| author | Ahmed, Ziyan S. Sherin, Rinsha P. V. Fonseca, Tatiana L. Hoang, Thanh D. Shakir, Mohamed K. M. |
| author_facet | Ahmed, Ziyan S. Sherin, Rinsha P. V. Fonseca, Tatiana L. Hoang, Thanh D. Shakir, Mohamed K. M. |
| author_sort | Ahmed, Ziyan S. |
| collection | PubMed |
| description | We report a 54‐year‐old man with treatment‐resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism. |
| format | Online Article Text |
| id | pubmed-9005678 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-90056782022-04-15 Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy Ahmed, Ziyan S. Sherin, Rinsha P. V. Fonseca, Tatiana L. Hoang, Thanh D. Shakir, Mohamed K. M. Clin Case Rep Case Reports We report a 54‐year‐old man with treatment‐resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism. John Wiley and Sons Inc. 2022-04-12 /pmc/articles/PMC9005678/ /pubmed/35432999 http://dx.doi.org/10.1002/ccr3.5651 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Case Reports Ahmed, Ziyan S. Sherin, Rinsha P. V. Fonseca, Tatiana L. Hoang, Thanh D. Shakir, Mohamed K. M. Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy |
| title | Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy |
| title_full | Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy |
| title_fullStr | Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy |
| title_full_unstemmed | Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy |
| title_short | Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy |
| title_sort | improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with lt3 therapy |
| topic | Case Reports |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005678/ https://www.ncbi.nlm.nih.gov/pubmed/35432999 http://dx.doi.org/10.1002/ccr3.5651 |
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