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Application of per-Residue Energy Decomposition to Design Peptide Inhibitors of PSD95 GK Domain

Specific interaction between the postsynaptic density protein 95 (PSD95) and synapse-associated protein 90/postsynaptic density 95–associated protein (SAPAP) is crucial for excitatory synaptic development and plasticity. Designing inhibitors that target the guanylate kinase (GK) domain of PSD95, whi...

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Detalles Bibliográficos
Autores principales:	Tian, Miao, Li, Hongwei, Yan, Xiao, Gu, Jing, Zheng, Pengfei, Luo, Sulan, Zhangsun, Dongting, Chen, Qiong, Ouyang, Qin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005747/ https://www.ncbi.nlm.nih.gov/pubmed/35433833 http://dx.doi.org/10.3389/fmolb.2022.848353

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