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Conformational Variation in Enzyme Catalysis: A Structural Study on Catalytic Residues

Conformational variation in catalytic residues can be captured as alternative snapshots in enzyme crystal structures. Addressing the question of whether active site flexibility is an intrinsic and essential property of enzymes for catalysis, we present a comprehensive study on the 3D variation of ac...

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Detalles Bibliográficos
Autores principales: Riziotis, Ioannis G., Ribeiro, António J.M., Borkakoti, Neera, Thornton, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005782/
https://www.ncbi.nlm.nih.gov/pubmed/35240125
http://dx.doi.org/10.1016/j.jmb.2022.167517