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Conformational Variation in Enzyme Catalysis: A Structural Study on Catalytic Residues
Conformational variation in catalytic residues can be captured as alternative snapshots in enzyme crystal structures. Addressing the question of whether active site flexibility is an intrinsic and essential property of enzymes for catalysis, we present a comprehensive study on the 3D variation of ac...
Autores principales: | Riziotis, Ioannis G., Ribeiro, António J.M., Borkakoti, Neera, Thornton, Janet M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005782/ https://www.ncbi.nlm.nih.gov/pubmed/35240125 http://dx.doi.org/10.1016/j.jmb.2022.167517 |
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