The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli

Our previous work using a murine model of pyelonephritis demonstrated that the C5a/C5aR1 axis plays a pathogenic role in acute kidney infection. In this study, we report that the C5a/C5aR1 axis also plays a pathogenic role in acute bladder infection. C5aR1-deficient mice had reduced bladder bacteria...

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Detalles Bibliográficos
Autores principales: Wu, Kun-Yi, Cao, Bo, Wang, Chun-Xuan, Yang, Xue-Ling, Zhao, Shu-Juan, Diao, Teng-Yue, Lin, Li-Rong, Zhao, Guo-Xiu, Zhou, Wuding, Yang, Ju-Rong, Li, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005882/
https://www.ncbi.nlm.nih.gov/pubmed/35433513
http://dx.doi.org/10.3389/fcimb.2022.824505

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