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GM-CSF secreting leukemia cell vaccination for MDS/AML after allogeneic HSCT: a randomized, double-blinded, phase 2 trial

Vaccination using irradiated, adenovirus transduced autologous myeloblasts to secrete granulocyte–macrophage colony-stimulating factor (GVAX) early after allogeneic hematopoietic stem cell transplantation (HSCT) can induce potent immune responses. We conducted a randomized phase 2 trial of GVAX afte...

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Detalles Bibliográficos
Autores principales:	Ho, Vincent T., Kim, Haesook T., Brock, Jennifer, Galinsky, Ilene, Daley, Heather, Reynolds, Carol, Weber, Augustine, Pozdnyakova, Olga, Severgnini, Mariano, Nikiforow, Sarah, Cutler, Corey, Koreth, John, Alyea, Edwin P., Antin, Joseph H., Gooptu, Mahasweta, Romee, Rizwan, Shapiro, Roman, Chen, Yi-Bin, Rosenblatt, Jacalyn, Avigan, David, Hodi, F. Stephen, Dranoff, Glenn, Wu, Catherine J., Ritz, Jerome, Soiffer, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Immunobiology and Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006263/ https://www.ncbi.nlm.nih.gov/pubmed/34807983 http://dx.doi.org/10.1182/bloodadvances.2021006255

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