A somatic UBA2 variant preceded ETV6-RUNX1 in the concordant BCP-ALL of monozygotic twins

Genetic analysis of leukemic clones in monozygotic twins with concordant acute lymphoblastic leukemia (ALL) has proved a unique opportunity to gain insight into the molecular phylogenetics of leukemogenesis. Using whole-genome sequencing, we characterized constitutional and somatic single nucleotide...

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Detalles Bibliográficos
Autores principales: Bang, Benedicte, Eisfeldt, Jesper, Barbany, Gisela, Harila-Saari, Arja, Heyman, Mats, Zachariadis, Vasilios, Taylan, Fulya, Nordgren, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006272/
https://www.ncbi.nlm.nih.gov/pubmed/34982829
http://dx.doi.org/10.1182/bloodadvances.2021005703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006272/
https://www.ncbi.nlm.nih.gov/pubmed/34982829
http://dx.doi.org/10.1182/bloodadvances.2021005703

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