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SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia
Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subtype of B-cell ALL characterized by a gene expression profile resembling Philadelphia chromosome–positive ALL (Ph(+) ALL) in the absence of BCR-ABL1. Tyrosine kinase–activating fusions, some involving ABL1, are recurren...
Autores principales: | Brown, Lauren M., Hediyeh-zadeh, Soroor, Sadras, Teresa, Huckstep, Hannah, Sandow, Jarrod J., Bartolo, Ray C., Kosasih, Hansen J., Davidson, Nadia M., Schmidt, Breon, Bjelosevic, Stefan, Johnstone, Ricky, Webb, Andrew I., Khaw, Seong L., Oshlack, Alicia, Davis, Melissa J., Ekert, Paul G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006296/ https://www.ncbi.nlm.nih.gov/pubmed/35061886 http://dx.doi.org/10.1182/bloodadvances.2021006076 |
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