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Targeting CD70 in cutaneous T-cell lymphoma using an antibody-drug conjugate in patient-derived xenograft models

CD70 is a member of the tumor necrosis factor receptor superfamily. Emerging data indicate that CD70 may be a suitable target for various malignancies. We investigated the expression of CD70 in cutaneous and systemic T-cell lymphomas and conducted preclinical studies of SGN-CD70A, a CD70-directed an...

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Detalles Bibliográficos
Autores principales:	Wu, Chi-Heng, Wang, Linlin, Yang, Chen-Yen, Wen, Kwun Wah, Hinds, Brian, Gill, Ryan, McCormick, Frank, Moasser, Mark, Pincus, Laura, Ai, Weiyun Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Lymphoid Neoplasia
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006301/ https://www.ncbi.nlm.nih.gov/pubmed/34872108 http://dx.doi.org/10.1182/bloodadvances.2021005714

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