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Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))
Background: Ozurdex(®) (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006423/ https://www.ncbi.nlm.nih.gov/pubmed/35465301 http://dx.doi.org/10.3205/oc000195 |
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author | Depla, Jozef Adelson M. Veckeneer, Marc Bleyen, Isabel |
author_facet | Depla, Jozef Adelson M. Veckeneer, Marc Bleyen, Isabel |
author_sort | Depla, Jozef Adelson M. |
collection | PubMed |
description | Background: Ozurdex(®) (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but troublesome due to its fragility. Several techniques exist, but elaborate setup and specialized surgical skills that are required may cause delay in treatment. We report a novel technique that avoids these shortcomings. Case presentation: A 59-year-old woman presented to the emergency department with visual loss due to an anterior chamber-migrated DEX implant and corneal edema. Using an ophthalmic viscosurgical device (OVD) and a bent 19-gauge needle, the implant has promptly been removed in a one-minute procedure under topical anesthesia. Conclusion: Aspirating an anterior chamber-migrated DEX implant using a 19-gauge bent needle is a cost-effective, time-efficient and safe technique, not requiring specialized surgical skills. |
format | Online Article Text |
id | pubmed-9006423 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-90064232022-04-21 Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) Depla, Jozef Adelson M. Veckeneer, Marc Bleyen, Isabel GMS Ophthalmol Cases Article Background: Ozurdex(®) (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but troublesome due to its fragility. Several techniques exist, but elaborate setup and specialized surgical skills that are required may cause delay in treatment. We report a novel technique that avoids these shortcomings. Case presentation: A 59-year-old woman presented to the emergency department with visual loss due to an anterior chamber-migrated DEX implant and corneal edema. Using an ophthalmic viscosurgical device (OVD) and a bent 19-gauge needle, the implant has promptly been removed in a one-minute procedure under topical anesthesia. Conclusion: Aspirating an anterior chamber-migrated DEX implant using a 19-gauge bent needle is a cost-effective, time-efficient and safe technique, not requiring specialized surgical skills. German Medical Science GMS Publishing House 2022-03-22 /pmc/articles/PMC9006423/ /pubmed/35465301 http://dx.doi.org/10.3205/oc000195 Text en Copyright © 2022 Depla et al. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Depla, Jozef Adelson M. Veckeneer, Marc Bleyen, Isabel Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) |
title | Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) |
title_full | Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) |
title_fullStr | Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) |
title_full_unstemmed | Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) |
title_short | Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) |
title_sort | active removal of anterior segment-migrated dexamethasone implant (ozurdex(®)) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006423/ https://www.ncbi.nlm.nih.gov/pubmed/35465301 http://dx.doi.org/10.3205/oc000195 |
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