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Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))

Background: Ozurdex(®) (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but...

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Detalles Bibliográficos
Autores principales: Depla, Jozef Adelson M., Veckeneer, Marc, Bleyen, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006423/
https://www.ncbi.nlm.nih.gov/pubmed/35465301
http://dx.doi.org/10.3205/oc000195
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author Depla, Jozef Adelson M.
Veckeneer, Marc
Bleyen, Isabel
author_facet Depla, Jozef Adelson M.
Veckeneer, Marc
Bleyen, Isabel
author_sort Depla, Jozef Adelson M.
collection PubMed
description Background: Ozurdex(®) (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but troublesome due to its fragility. Several techniques exist, but elaborate setup and specialized surgical skills that are required may cause delay in treatment. We report a novel technique that avoids these shortcomings. Case presentation: A 59-year-old woman presented to the emergency department with visual loss due to an anterior chamber-migrated DEX implant and corneal edema. Using an ophthalmic viscosurgical device (OVD) and a bent 19-gauge needle, the implant has promptly been removed in a one-minute procedure under topical anesthesia. Conclusion: Aspirating an anterior chamber-migrated DEX implant using a 19-gauge bent needle is a cost-effective, time-efficient and safe technique, not requiring specialized surgical skills.
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spelling pubmed-90064232022-04-21 Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®)) Depla, Jozef Adelson M. Veckeneer, Marc Bleyen, Isabel GMS Ophthalmol Cases Article Background: Ozurdex(®) (Allergan plc., Dublin, Ireland) is an intravitreal sustained-release dexamethasone (DEX) implant. The implant has been reported to migrate into the anterior chamber, potentially causing corneal decompensation. Prompt removal or relocation in the vitreous cavity is advised but troublesome due to its fragility. Several techniques exist, but elaborate setup and specialized surgical skills that are required may cause delay in treatment. We report a novel technique that avoids these shortcomings. Case presentation: A 59-year-old woman presented to the emergency department with visual loss due to an anterior chamber-migrated DEX implant and corneal edema. Using an ophthalmic viscosurgical device (OVD) and a bent 19-gauge needle, the implant has promptly been removed in a one-minute procedure under topical anesthesia. Conclusion: Aspirating an anterior chamber-migrated DEX implant using a 19-gauge bent needle is a cost-effective, time-efficient and safe technique, not requiring specialized surgical skills. German Medical Science GMS Publishing House 2022-03-22 /pmc/articles/PMC9006423/ /pubmed/35465301 http://dx.doi.org/10.3205/oc000195 Text en Copyright © 2022 Depla et al. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Depla, Jozef Adelson M.
Veckeneer, Marc
Bleyen, Isabel
Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))
title Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))
title_full Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))
title_fullStr Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))
title_full_unstemmed Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))
title_short Active removal of anterior segment-migrated dexamethasone implant (Ozurdex(®))
title_sort active removal of anterior segment-migrated dexamethasone implant (ozurdex(®))
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006423/
https://www.ncbi.nlm.nih.gov/pubmed/35465301
http://dx.doi.org/10.3205/oc000195
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