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Novel pathological predictive factors for extranodal extension in oral squamous cell carcinoma: a retrospective cohort study based on tumor budding, desmoplastic reaction, tumor-infiltrating lymphocytes, and depth of invasion
BACKGROUND: Extranodal extension (ENE) is a poor prognostic factor for oral squamous cell carcinoma (OSCC). Identifying ENE by clinical and/or radiological examination is difficult, thereby leading to unnecessary neck dissections. Currently, no definitive predictors are available for ENE. Thus, we a...
Autores principales: | Noda, Yuri, Ishida, Mitsuaki, Ueno, Yasuhiro, Fujisawa, Takuo, Iwai, Hiroshi, Tsuta, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006434/ https://www.ncbi.nlm.nih.gov/pubmed/35418058 http://dx.doi.org/10.1186/s12885-022-09393-8 |
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