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Using Structure-guided Fragment-Based Drug Discovery to Target Pseudomonas aeruginosa Infections in Cystic Fibrosis

Cystic fibrosis (CF) is progressive genetic disease that predisposes lungs and other organs to multiple long-lasting microbial infections. Pseudomonas aeruginosa is the most prevalent and deadly pathogen among these microbes. Lung function of CF patients worsens following chronic infections with P....

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Detalles Bibliográficos
Autores principales:	Arif, Sheikh Mohammed, Floto, R. Andres, Blundell, Tom L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006449/ https://www.ncbi.nlm.nih.gov/pubmed/35433835 http://dx.doi.org/10.3389/fmolb.2022.857000

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