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The effect of a loading dose of meropenem on outcomes of patients with sepsis treated by continuous renal replacement: study protocol for a randomized controlled trial

BACKGROUND: Sepsis and continuous renal replacement therapy (CRRT) are both responsible for the alterations of the pharmacokinetics of antibiotics. For patients with sepsis receiving CRRT, the serum concentrations of meropenem in the early phase (< 48 h) was significantly lower than that in the l...

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Detalles Bibliográficos
Autores principales:	Ni, Sui-Qing, Teng, Wen-Bing, Fu, Yong-Hong, Su, Wei, Yang, Zhi, Cai, Jie, Xu, Jin-Nuo, Deng, Xiao-Ying, Liu, Xiang-Fang, Fu, Sheng-Nan, Zeng, Jun, Zhang, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006454/ https://www.ncbi.nlm.nih.gov/pubmed/35413886 http://dx.doi.org/10.1186/s13063-022-06264-2

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