HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme

BACKGROUND: Glioblastoma multiforme (GBM) is the most common high-grade malignant brain tumour in adults and arises from the glial cells in the brain. The prognosis of treated GBM remains very poor with 5-year survival rates of 5%, a figure which has not improved over the last few decades. Currently...

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Detalles Bibliográficos
Autores principales: Arunachalam, Einthavy, Rogers, William, Simpson, Guy R., Möller-Levet, Carla, Bolton, Gemma, Ismael, Mohammed, Smith, Christopher, Keegen, Karl, Bagwan, Izhar, Brend, Tim, Short, Susan C., Hong, Bangxing, Otani, Yoshihiro, Kaur, Balveen, Annels, Nicola, Morgan, Richard, Pandha, Hardev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006463/
https://www.ncbi.nlm.nih.gov/pubmed/35418059
http://dx.doi.org/10.1186/s12885-022-09466-8

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