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Lymph node-targeted neoantigen nanovaccines potentiate anti-tumor immune responses of post-surgical melanoma

BACKGROUND: Neoantigens are considered ideal targets for immunotherapy, especially tumor vaccine, because of their strong specificity and immunogenicity. Here, we developed a neoantigen nanovaccine used liposomes with lymph-node targeting characteristic. METHODS: Our nanovaccine was composed of neoa...

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Detalles Bibliográficos
Autores principales: Chu, Yanhong, Qian, Lingyu, Ke, Yaohua, Feng, Xiaoyu, Chen, Xinjie, Liu, Fangcen, Yu, Lixia, Zhang, Lianru, Tao, Yaping, Xu, Rui, Wei, Jia, Liu, Baorui, Liu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006542/
https://www.ncbi.nlm.nih.gov/pubmed/35418151
http://dx.doi.org/10.1186/s12951-022-01397-7