Antigenic analysis of the HIV-1 envelope trimer implies small differences between structural states 1 and 2

The conformationally dynamic HIV-1 envelope trimer (Env) is the target of broadly neutralizing antibodies (bnAbs) that block viral entry. Single-molecule Förster resonance energy transfer (smFRET) has revealed that HIV-1 Env exists in at least three conformational states on the virion. Prior to comp...

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Detalles Bibliográficos
Autores principales: Cale, Evan M., Driscoll, Jefferson I., Lee, Myungjin, Gorman, Jason, Zhou, Tongqing, Lu, Maolin, Geng, Hui, Lai, Yen-Ting, Chuang, Gwo-Yu, Doria-Rose, Nicole A., Mothes, Walther, Kwong, Peter D., Mascola, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006658/
https://www.ncbi.nlm.nih.gov/pubmed/35283191
http://dx.doi.org/10.1016/j.jbc.2022.101819

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