Cargando…

Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment

OBJECTIVES: To investigate all-cause and cause-specific mortality risks, including deaths from external, cardiovascular and cancer causes, among deployed Nordic military veterans in comparison to the general population in each country. DESIGN: Pooled analysis. SETTING: Denmark, Norway, Finland and S...

Descripción completa

Detalles Bibliográficos
Autores principales: Pethrus, Carl-Martin, Vedtofte, Mia Sadowa, Neovius, Kristian, Borud, Einar K, Neovius, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006836/
https://www.ncbi.nlm.nih.gov/pubmed/35414543
http://dx.doi.org/10.1136/bmjopen-2021-052313
_version_ 1784686744006819840
author Pethrus, Carl-Martin
Vedtofte, Mia Sadowa
Neovius, Kristian
Borud, Einar K
Neovius, Martin
author_facet Pethrus, Carl-Martin
Vedtofte, Mia Sadowa
Neovius, Kristian
Borud, Einar K
Neovius, Martin
author_sort Pethrus, Carl-Martin
collection PubMed
description OBJECTIVES: To investigate all-cause and cause-specific mortality risks, including deaths from external, cardiovascular and cancer causes, among deployed Nordic military veterans in comparison to the general population in each country. DESIGN: Pooled analysis. SETTING: Denmark, Norway, Finland and Sweden. PARTICIPANTS: Military veterans deployed between 1990 and 2010 were followed via nationwide registers and compared with age-sex-calendar-year-specific rates in the general population using pooled standardised mortality ratios (SMRs). MAIN OUTCOMES: All-cause and cause-specific mortality retrieved from each country’s Causes of Death Register, including deaths from external, cardiovascular and cancer causes. RESULTS: Among 83 584 veterans 1152 deaths occurred of which 343 were from external causes (including 203 suicides and 129 traffic/transport accidents), 134 from cardiovascular causes and 297 from neoplasms. Veterans had a lower risk of death from any cause (pooled SMR 0.58, 95% CI 0.52 to 0.64), external causes (0.71, 95% CI 0.64 to 0.79), suicide (0.77, 95% CI 0.67 to 0.89), cardiovascular causes (0.54, 95% CI 0.46 to 0.64) and neoplasms (0.78, 95% CI 0.70 to 0.88). There was no difference regarding traffic/transport accidents for the whole period (1.10, 95% CI 0.92 to 1.31) but the pooled point estimate was elevated, though not statistically significant, during the first 5 years (1.17, 95% CI 0.89 to 1.53) but not thereafter (1.01, 95% CI 0.77 to 1.34). For all other causes of death, except suicide, statistically significantly lower risk among veterans was observed both during the first 5 years and thereafter. For suicide, no difference was observed beyond 5 years. Judged from the country-specific SMR estimates, there was a high degree of consistency although statistically significant heterogeneity was found for all-cause mortality. CONCLUSIONS: Nordic military veterans had lower overall and cause-specific mortality than the general population for most outcomes, as expected given the predeployment selection process. Though uncommon, fatal traffic/transport accidents were an exception with no difference between deployed military veterans and the general population.
format Online
Article
Text
id pubmed-9006836
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-90068362022-05-02 Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment Pethrus, Carl-Martin Vedtofte, Mia Sadowa Neovius, Kristian Borud, Einar K Neovius, Martin BMJ Open Epidemiology OBJECTIVES: To investigate all-cause and cause-specific mortality risks, including deaths from external, cardiovascular and cancer causes, among deployed Nordic military veterans in comparison to the general population in each country. DESIGN: Pooled analysis. SETTING: Denmark, Norway, Finland and Sweden. PARTICIPANTS: Military veterans deployed between 1990 and 2010 were followed via nationwide registers and compared with age-sex-calendar-year-specific rates in the general population using pooled standardised mortality ratios (SMRs). MAIN OUTCOMES: All-cause and cause-specific mortality retrieved from each country’s Causes of Death Register, including deaths from external, cardiovascular and cancer causes. RESULTS: Among 83 584 veterans 1152 deaths occurred of which 343 were from external causes (including 203 suicides and 129 traffic/transport accidents), 134 from cardiovascular causes and 297 from neoplasms. Veterans had a lower risk of death from any cause (pooled SMR 0.58, 95% CI 0.52 to 0.64), external causes (0.71, 95% CI 0.64 to 0.79), suicide (0.77, 95% CI 0.67 to 0.89), cardiovascular causes (0.54, 95% CI 0.46 to 0.64) and neoplasms (0.78, 95% CI 0.70 to 0.88). There was no difference regarding traffic/transport accidents for the whole period (1.10, 95% CI 0.92 to 1.31) but the pooled point estimate was elevated, though not statistically significant, during the first 5 years (1.17, 95% CI 0.89 to 1.53) but not thereafter (1.01, 95% CI 0.77 to 1.34). For all other causes of death, except suicide, statistically significantly lower risk among veterans was observed both during the first 5 years and thereafter. For suicide, no difference was observed beyond 5 years. Judged from the country-specific SMR estimates, there was a high degree of consistency although statistically significant heterogeneity was found for all-cause mortality. CONCLUSIONS: Nordic military veterans had lower overall and cause-specific mortality than the general population for most outcomes, as expected given the predeployment selection process. Though uncommon, fatal traffic/transport accidents were an exception with no difference between deployed military veterans and the general population. BMJ Publishing Group 2022-04-11 /pmc/articles/PMC9006836/ /pubmed/35414543 http://dx.doi.org/10.1136/bmjopen-2021-052313 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Epidemiology
Pethrus, Carl-Martin
Vedtofte, Mia Sadowa
Neovius, Kristian
Borud, Einar K
Neovius, Martin
Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment
title Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment
title_full Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment
title_fullStr Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment
title_full_unstemmed Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment
title_short Pooled analysis of all-cause and cause-specific mortality among Nordic military veterans following international deployment
title_sort pooled analysis of all-cause and cause-specific mortality among nordic military veterans following international deployment
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006836/
https://www.ncbi.nlm.nih.gov/pubmed/35414543
http://dx.doi.org/10.1136/bmjopen-2021-052313
work_keys_str_mv AT pethruscarlmartin pooledanalysisofallcauseandcausespecificmortalityamongnordicmilitaryveteransfollowinginternationaldeployment
AT vedtoftemiasadowa pooledanalysisofallcauseandcausespecificmortalityamongnordicmilitaryveteransfollowinginternationaldeployment
AT neoviuskristian pooledanalysisofallcauseandcausespecificmortalityamongnordicmilitaryveteransfollowinginternationaldeployment
AT borudeinark pooledanalysisofallcauseandcausespecificmortalityamongnordicmilitaryveteransfollowinginternationaldeployment
AT neoviusmartin pooledanalysisofallcauseandcausespecificmortalityamongnordicmilitaryveteransfollowinginternationaldeployment