Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression

Immunosuppressive factors in the tumor microenvironment (TME) impair T cell function and limit the antitumor immune response. T cell surface receptors and surface proteins that influence interactions and function in the TME are proven targets for cancer immunotherapy. However, how the entire surface...

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Detalles Bibliográficos
Autores principales: Byrnes, James R., Weeks, Amy M., Shifrut, Eric, Carnevale, Julia, Kirkemo, Lisa, Ashworth, Alan, Marson, Alexander, Wells, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006863/
https://www.ncbi.nlm.nih.gov/pubmed/35217172
http://dx.doi.org/10.1016/j.mcpro.2022.100217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006863/
https://www.ncbi.nlm.nih.gov/pubmed/35217172
http://dx.doi.org/10.1016/j.mcpro.2022.100217

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