Cargando…

Autoimmune Disease Associated CLEC16A Variants Convey Risk of Parkinson’s Disease in Han Chinese

CLEC16A is a membrane-associated endosomal protein implicated in regulating autophagy and antigen presentation. Its genetic variants are broadly associated with multiple autoimmune diseases. Parkinson’s disease (PD), which undergoes autophagy disruption and neuroinflammation, has been clinically obs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Hui-Hui, Cui, Lei, Jiang, Xiao-Xia, Song, Ya-Dan, Liu, Shu-Shu, Wu, Ke-Yun, Dong, Hao-Jia, Mao, Miao, Ovlyakulov, Begench, Wu, Hong-Mei, Zhu, Jian-Hong, Zhang, Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007333/ https://www.ncbi.nlm.nih.gov/pubmed/35432448 http://dx.doi.org/10.3389/fgene.2022.856493

Ejemplares similares

The cis-Regulatory Element of SNCA Intron 4 Modulates Susceptibility to Parkinson’s Disease in Han Chinese
por: Zhu, Shi-Guo, et al.
Publicado: (2020)

Polymorphisms of CLEC16A Region and Autoimmune Thyroid Diseases
por: Muhali, Fatuma-Said, et al.
Publicado: (2014)

Association Analyses of Autonomic Dysfunction and Sympathetic Skin Response in Motor Subtypes of Parkinson's Disease
por: Wang, Jian-Yong, et al.
Publicado: (2020)

Overlapping anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis with neuromyelitis optica spectrum disorders: a case report
por: Pan, Jialin, et al.
Publicado: (2022)

CLEC16A variants conferred a decreased risk to allergic rhinitis in the Chinese population
por: Niu, Yongliang, et al.
Publicado: (2022)

CLEC16A—An Emerging Master Regulator of Autoimmunity and Neurodegeneration
por: Pandey, Rahul, et al.
Publicado: (2023)

The Autoimmune Disorder Susceptibility Gene CLEC16A Restrains NK Cell Function in YTS NK Cell Line and Clec16a Knockout Mice
por: Pandey, Rahul, et al.
Publicado: (2019)

Genetic analysis of the TMEM230 gene in Chinese Han patients with Parkinson’s disease
por: Shi, Chang-he, et al.
Publicado: (2017)

A cross‐sectional survey on occupational stress and associated dyslipidemia among medical staff in tertiary public hospitals in Wenzhou, China
por: Zhang, Hui, et al.
Publicado: (2020)

Gene-wide significant association analyses of DNMT1 genetic variants with Parkinson’s disease
por: Wang, Jian-Yong, et al.
Publicado: (2023)

ACTB Variants Confer the Genetic Susceptibility to Diabetic Kidney Disease in a Han Chinese Population
por: Li, Mengxia, et al.
Publicado: (2019)

JAK/STAT inhibitor therapy partially rescues the lipodystrophic autoimmune phenotype in Clec16a KO mice
por: Pandey, Rahul, et al.
Publicado: (2021)

Novel Mutations Associated With Various Types of Corneal Dystrophies in a Han Chinese Population
por: Zhang, Jing, et al.
Publicado: (2019)

Identification of DNAH17 Variants in Han-Chinese Patients With Left–Right Asymmetry Disorders
por: Yu, Xuehui, et al.
Publicado: (2022)

ALDH1A1 Genetic Variations May Modulate Risk of Parkinson’s Disease in Han Chinese Population
por: Fan, Hui-Hui, et al.
Publicado: (2021)

Milk as a Conveyer of Disease
por: Cooper, T. J.
Publicado: (1902)

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells
por: Leikfoss, Ingvild S., et al.
Publicado: (2015)

Sex-Biased Population Admixture Mediated Subsistence Strategy Transition of Heishuiguo People in Han Dynasty Hexi Corridor
por: Xiong, Jianxue, et al.
Publicado: (2022)

Identification of immune signatures in Parkinson’s disease based on co-expression networks
por: Dong, Xiaolin, et al.
Publicado: (2023)

Polymorphisms in ERAP1 and ERAP2 Genes Are Associated With Tuberculosis in the Han Chinese
por: Zhang, Shuqiong, et al.
Publicado: (2020)

Case report: Analysis of novel compound heterozygous TPP1 variants in a Chinese patient with neuronal ceroid lipofuscinosis type 2
por: Miao, Sui-Bing, et al.
Publicado: (2022)

Haplotype association analysis of combining unrelated case-control and triads with consideration of population stratification
por: Wen, Shu-Hui, et al.
Publicado: (2014)

Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival
por: Redmann, Veronika, et al.
Publicado: (2016)

Inducible knockout of Clec16a in mice results in sensory neurodegeneration
por: Hain, Heather S., et al.
Publicado: (2021)

Validation of Susceptibility Loci for Vitiligo Identified by GWAS in the Chinese Han Population
por: Cheng, Lu, et al.
Publicado: (2020)

Diversity of clinical phenotypes in a cohort of Han Chinese patients with PAX6 variants
por: Huang, Lijuan, et al.
Publicado: (2023)

Association of SGK1 Polymorphisms With Susceptibility to Coronary Heart Disease in Chinese Han Patients With Comorbid Depression
por: Han, Wenxiu, et al.
Publicado: (2019)

Identification of Clec4b as a novel regulator of bystander activation of auto-reactive T cells and autoimmune disease
por: Bäckdahl, Liselotte, et al.
Publicado: (2020)

CLEC5A mediates Zika virus-induced testicular damage
por: Wang, Hsin-Wei, et al.
Publicado: (2023)

Epigenetics and autoimmune diseases: the X chromosome-nucleolus nexus
por: Brooks, Wesley H., et al.
Publicado: (2015)

Characteristics of malignant tumors of digestive system and autoimmune diseases
por: Yin, Hang, et al.
Publicado: (2023)

Interaction of Wnt pathway related variants with type 2 diabetes in a Chinese Han population
por: Zhou, Jian-Bo, et al.
Publicado: (2015)

Association of NLRP3 rs35829419 and rs10754558 Polymorphisms With Risks of Autoimmune Diseases: A Systematic Review and Meta-Analysis
por: Wu, Zubo, et al.
Publicado: (2021)

Association of Variants in PLD1, 3p24.1, and 10q11.21 Regions With Hirschsprung’s Disease in Han Chinese Population
por: Niu, Wei-Bo, et al.
Publicado: (2020)

Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn’s disease
por: Elleisy, Nagi, et al.
Publicado: (2020)

A synthetic kinematic index of trunk displacement conveying the overall motor condition in Parkinson’s disease
por: Troisi Lopez, Emahnuel, et al.
Publicado: (2021)

Parkinson’s Disease in Teneurin Transmembrane Protein 4 (TENM4) Mutation Carriers
por: Pu, Jia-Li, et al.
Publicado: (2020)

The Same Chromosome 9p21.3 Locus Is Associated With Type 2 Diabetes and Coronary Artery Disease in a Chinese Han Population
por: Cheng, Xiang, et al.
Publicado: (2011)

An Update Evolving View of Copy Number Variations in Autoimmune Diseases
por: Song, Rong-hua, et al.
Publicado: (2022)

From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A
por: Berge, Tone, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jm9i7d4i7k8ku8nh5gqhar6and