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Retinoid-X receptor agonists increase thyroid hormone competence in lower jaw remodeling of pre-metamorphic Xenopus laevis tadpoles

Thyroid hormone (TH) signaling plays critical roles during vertebrate development, including regulation of skeletal and cartilage growth. TH acts through its receptors (TRs), nuclear hormone receptors (NRs) that heterodimerize with Retinoid-X receptors (RXRs), to regulate gene expression. A defining...

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Detalles Bibliográficos
Autores principales: Mengeling, Brenda J., Vetter, Lara F., Furlow, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007347/
https://www.ncbi.nlm.nih.gov/pubmed/35417489
http://dx.doi.org/10.1371/journal.pone.0266946