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Heteroplasmic mitochondrial DNA variants in cardiovascular diseases

Mitochondria are implicated in the pathogenesis of cardiovascular diseases (CVDs) but the reasons for this are not well understood. Maternally-inherited population variants of mitochondrial DNA (mtDNA) which affect all mtDNA molecules (homoplasmic) are associated with cardiometabolic traits and the...

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Detalles Bibliográficos
Autores principales:	Calabrese, Claudia, Pyle, Angela, Griffin, Helen, Coxhead, Jonathan, Hussain, Rafiqul, Braund, Peter S, Li, Linxin, Burgess, Annette, Munroe, Patricia B, Little, Louis, Warren, Helen R, Cabrera, Claudia, Hall, Alistair, Caulfield, Mark J, Rothwell, Peter M, Samani, Nilesh J, Hudson, Gavin, Chinnery, Patrick F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007378/ https://www.ncbi.nlm.nih.gov/pubmed/35363781 http://dx.doi.org/10.1371/journal.pgen.1010068

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