Glucocorticoid-induced loss of beneficial gut bacterial extracellular vesicles is associated with the pathogenesis of osteonecrosis

Osteonecrosis of the femoral head (ONFH) commonly occurs after glucocorticoid (GC) therapy. The gut microbiota (GM) participates in regulating host health, and its composition can be altered by GC. Here, this study demonstrates that cohousing with healthy mice or colonization with GM from normal mic...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Yuan, Rao, Shan-Shan, Yue, Tao, Tan, Yi-Juan, Yin, Hao, Chen, Ling-Jiao, Luo, Ming-Jie, Wang, Zun, Wang, Yi-Yi, Hong, Chun-Gu, Qian, Yu-Xuan, He, Ze-Hui, Liu, Jiang-Hua, Yang, Fei, Huang, Fei-Yu, Tang, Si-Yuan, Xie, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007505/
https://www.ncbi.nlm.nih.gov/pubmed/35417243
http://dx.doi.org/10.1126/sciadv.abg8335

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