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The role of AMPK-dependent pathways in cellular and molecular mechanisms of metformin: a new perspective for treatment and prevention of diseases
Metformin can suppress gluconeogenesis and reduce blood sugar by activating adenosine monophosphate-activated protein kinase (AMPK) and inducing small heterodimer partner (SHP) expression in the liver cells. The main mechanism of metformin’s action is related to its activation of the AMPK enzyme and...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer International Publishing
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007580/ https://www.ncbi.nlm.nih.gov/pubmed/35419709 http://dx.doi.org/10.1007/s10787-022-00980-6 |