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A workflow for the joint modeling of longitudinal and event data in the development of therapeutics: Tools, statistical methods, and diagnostics

Clinical trials investigate treatment endpoints that usually include measurements of pharmacodynamic and efficacy biomarkers in early‐phase studies and patient‐reported outcomes as well as event risks or rates in late‐phase studies. In recent years, a systematic trend in clinical trial data analytic...

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Detalles Bibliográficos
Autores principales: Zhudenkov, Kirill, Gavrilov, Sergey, Sofronova, Alina, Stepanov, Oleg, Kudryashova, Nataliya, Helmlinger, Gabriel, Peskov, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007602/
https://www.ncbi.nlm.nih.gov/pubmed/35064957
http://dx.doi.org/10.1002/psp4.12763

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