The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro

Arginines within the third intracellular loop of the C. elegans OCTR-1 and human ADRA2A receptors are methylated by the human protein arginine methyltransferase PRMT5 in vitro . Methylation of these residues could serve to modulate receptor signaling in vivo .

Detalles Bibliográficos
Autores principales: Bowitch, Alexander, Chinsky, Tyler M., Yu, Michael C., Ferkey, Denise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007614/
https://www.ncbi.nlm.nih.gov/pubmed/35622502
http://dx.doi.org/10.17912/micropub.biology.000546
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author Bowitch, Alexander
Chinsky, Tyler M.
Yu, Michael C.
Ferkey, Denise M.
author_facet Bowitch, Alexander
Chinsky, Tyler M.
Yu, Michael C.
Ferkey, Denise M.
author_sort Bowitch, Alexander
collection PubMed
description Arginines within the third intracellular loop of the C. elegans OCTR-1 and human ADRA2A receptors are methylated by the human protein arginine methyltransferase PRMT5 in vitro . Methylation of these residues could serve to modulate receptor signaling in vivo .
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spelling pubmed-90076142022-04-14 The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro Bowitch, Alexander Chinsky, Tyler M. Yu, Michael C. Ferkey, Denise M. MicroPubl Biol New Finding Arginines within the third intracellular loop of the C. elegans OCTR-1 and human ADRA2A receptors are methylated by the human protein arginine methyltransferase PRMT5 in vitro . Methylation of these residues could serve to modulate receptor signaling in vivo . Caltech Library 2022-03-23 /pmc/articles/PMC9007614/ /pubmed/35622502 http://dx.doi.org/10.17912/micropub.biology.000546 Text en Copyright: © 2022 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle New Finding
Bowitch, Alexander
Chinsky, Tyler M.
Yu, Michael C.
Ferkey, Denise M.
The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro
title The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro
title_full The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro
title_fullStr The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro
title_full_unstemmed The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro
title_short The C. elegans OCTR-1 and Human Alpha-2A Adrenergic Receptors are Methylated within the Third Intracellular Loop by Human PRMT5 in vitro
title_sort the c. elegans octr-1 and human alpha-2a adrenergic receptors are methylated within the third intracellular loop by human prmt5 in vitro
topic New Finding
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007614/
https://www.ncbi.nlm.nih.gov/pubmed/35622502
http://dx.doi.org/10.17912/micropub.biology.000546
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