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Selenium Supplementation Improved Cardiac Functions by Suppressing DNMT2-Mediated GPX1 Promoter DNA Methylation in AGE-Induced Heart Failure

OBJECTIVE: Advanced glycation end products (AGEs) are featured metabolites associated with diabetic cardiomyopathy which is characterized by heart failure caused by myocyte apoptosis. Selenium was proved cardioprotective. This study was aimed at investigating the therapeutic effects and underlying m...

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Detalles Bibliográficos
Autores principales:	Zhu, Huolan, Wang, Xiang, Meng, Xuyang, Kong, Yiya, Li, Yi, Yang, Chenguang, Guo, Ying, Wang, Xiqiang, Yang, Haini, Liu, Zhongwei, Wang, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007686/ https://www.ncbi.nlm.nih.gov/pubmed/35432721 http://dx.doi.org/10.1155/2022/5402997

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