Sulfasalazine decreases astrogliosis‐mediated seizure burden

OBJECTIVE: Previously, we reported that inhibition of the astrocytic cystine/glutamate antiporter system xc‐ (SXC), using sulfasalazine (SAS), decreased evoked excitatory signaling in three distinct hyperexcitability models ex vivo. The current study expands on this work by evaluating the in vivo ef...

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Detalles Bibliográficos
Autores principales: Alcoreza, Oscar, Jagarlamudi, Sai, Savoia, Andrew, Campbell, Susan L., Sontheimer, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007880/
https://www.ncbi.nlm.nih.gov/pubmed/35132640
http://dx.doi.org/10.1111/epi.17178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007880/
https://www.ncbi.nlm.nih.gov/pubmed/35132640
http://dx.doi.org/10.1111/epi.17178

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