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Combination gemcitabine and PD-L1xCD3 bispecific T cell engager (BiTE) enhances T lymphocyte cytotoxicity against cholangiocarcinoma cells
Cholangiocarcinoma (CCA) is a lethal cancer with rapid progression and poor survival. Novel and more effective therapies than those currently available are, therefore, urgently needed. Our research group previously reported the combination of gemcitabine and cytotoxic T lymphocytes to be more effect...
Autores principales: | Wathikthinnakon, Methi, Luangwattananun, Piriya, Sawasdee, Nunghathai, Chiawpanit, Chutipa, Lee, Vannajan Sanghiran, Nimmanpipug, Piyarat, Tragoolpua, Yingmanee, Rotarayanont, Siriphorn, Sangsuwannukul, Thanich, Phanthaphol, Nattaporn, Wutti-in, Yupanun, Somboonpatarakun, Chalermchai, Chieochansin, Thaweesak, Junking, Mutita, Sujjitjoon, Jatuporn, Yenchitsomanus, Pa-thai, Panya, Aussara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007942/ https://www.ncbi.nlm.nih.gov/pubmed/35418130 http://dx.doi.org/10.1038/s41598-022-09964-6 |
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