The impact of reproductive factors on DNA methylation-based telomere length in healthy breast tissue

Estrogen promotes breast tissue proliferation and telomerase activation. We investigated the effects of reproductive history on cell cycling and telomere length using a DNA methylation-based estimate of telomere length (DNAmTL) in breast and blood from healthy women donors. We demonstrate that DNAmT...

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Detalles Bibliográficos
Autores principales: Sehl, Mary E., Henry, Jill E., Storniolo, Anna Maria, Horvath, Steve, Ganz, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007943/
https://www.ncbi.nlm.nih.gov/pubmed/35418123
http://dx.doi.org/10.1038/s41523-022-00410-4

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