Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

Use of menopausal hormone therapy (MHT) is associated with increased risk for breast cancer. However, the relevant mechanisms and its interaction with genetic variants are not fully understood. We conducted a genome-wide interaction analysis between MHT use and genetic variants for breast cancer ris...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoliang, Kapoor, Pooja Middha, Auer, Paul L., Dennis, Joe, Dunning, Alison M., Wang, Qin, Lush, Michael, Michailidou, Kyriaki, Bolla, Manjeet K., Aronson, Kristan J., Murphy, Rachel A., Brooks-Wilson, Angela, Lee, Derrick G., Cordina-Duverger, Emilie, Guénel, Pascal, Truong, Thérèse, Mulot, Claire, Teras, Lauren R., Patel, Alpa V., Dossus, Laure, Kaaks, Rudolf, Hoppe, Reiner, Lo, Wing-Yee, Brüning, Thomas, Hamann, Ute, Czene, Kamila, Gabrielson, Marike, Hall, Per, Eriksson, Mikael, Jung, Audrey, Becher, Heiko, Couch, Fergus J., Larson, Nicole L., Olson, Janet E., Ruddy, Kathryn J., Giles, Graham G., MacInnis, Robert J., Southey, Melissa C., Le Marchand, Loic, Wilkens, Lynne R., Haiman, Christopher A., Olsson, Håkan, Augustinsson, Annelie, Krüger, Ute, Wagner, Philippe, Scott, Christopher, Winham, Stacey J., Vachon, Celine M., Perou, Charles M., Olshan, Andrew F., Troester, Melissa A., Hunter, David J., Eliassen, Heather A., Tamimi, Rulla M., Brantley, Kristen, Andrulis, Irene L., Figueroa, Jonine, Chanock, Stephen J., Ahearn, Thomas U., García-Closas, Montserrat, Evans, Gareth D., Newman, William G., van Veen, Elke M., Howell, Anthony, Wolk, Alicja, Håkansson, Niclas, Anton-Culver, Hoda, Ziogas, Argyrios, Jones, Michael E., Orr, Nick, Schoemaker, Minouk J., Swerdlow, Anthony J., Kitahara, Cari M., Linet, Martha, Prentice, Ross L., Easton, Douglas F., Milne, Roger L., Kraft, Peter, Chang-Claude, Jenny, Lindström, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007944/
https://www.ncbi.nlm.nih.gov/pubmed/35418701
http://dx.doi.org/10.1038/s41598-022-10121-2

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