Downregulation of REST in the cochlea contributes to age-related hearing loss via the p53 apoptosis pathway

Age-related hearing loss (AHL) is the most common sensory disorder amongst the elderly population. Although the degeneration of spiral ganglion neurons (SGNs) and hair cells (HCs) is considered to play a critical role in AHL, the mechanism has not been fully outlined. The repressor element 1-silenci...

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Detalles Bibliográficos
Autores principales: Li, Hongchen, Lu, Mingshun, Zhang, Haiwei, Wang, Shengnan, Wang, Fei, Ma, Xueya, Liu, Jiaxi, Li, Xinyu, Yang, Haichao, Shen, Haitao, Lv, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007975/
https://www.ncbi.nlm.nih.gov/pubmed/35418568
http://dx.doi.org/10.1038/s41419-022-04774-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007975/
https://www.ncbi.nlm.nih.gov/pubmed/35418568
http://dx.doi.org/10.1038/s41419-022-04774-0

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