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Data-driven learning how oncogenic gene expression locally alters heterocellular networks
Developing drugs increasingly relies on mechanistic modeling and simulation. Models that capture causal relations among genetic drivers of oncogenesis, functional plasticity, and host immunity complement wet experiments. Unfortunately, formulating such mechanistic cell-level models currently relies...
Autores principales: | Klinke, David J., Fernandez, Audry, Deng, Wentao, Razazan, Atefeh, Latifizadeh, Habibolla, Pirkey, Anika C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007999/ https://www.ncbi.nlm.nih.gov/pubmed/35418177 http://dx.doi.org/10.1038/s41467-022-29636-3 |
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