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Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism

Extracellular vesicle (EV)-mediated transfer of long non-coding RNAs (lncRNAs) has been reported to regulate chemoresistance in various cancers. We herein investigate the therapeutic potential of bioinformatically identified HOTAIR transferred by serum-derived EVs (serum-EVs) in temozolomide (TMZ) r...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaosong, Yu, Xiaojun, Xu, Haoran, Wei, Kang, Wang, Shanxi, Wang, Yingguang, Han, Junfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008004/ https://www.ncbi.nlm.nih.gov/pubmed/35418162 http://dx.doi.org/10.1038/s41419-022-04699-8

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