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Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle

OBJECTIVE: Current data regarding the roles of branched-chain amino acids (BCAA) in metabolic health are rather conflicting, as positive and negative effects have been attributed to their intake. METHODS: To address this, individual effects of leucine and valine were elucidated in vivo (C57BL/6JRj m...

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Detalles Bibliográficos
Autores principales:	Bishop, Christopher A., Machate, Tina, Henning, Thorsten, Henkel, Janin, Püschel, Gerhard, Weber, Daniela, Grune, Tilman, Klaus, Susanne, Weitkunat, Karolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008040/ https://www.ncbi.nlm.nih.gov/pubmed/35418570 http://dx.doi.org/10.1038/s41387-022-00200-8

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