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Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis

Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce cardiovascular mortality in patients with diabetes mellitus but the protective mechanism remains elusive. Here we demonstrated that the SGLT2 inhibitor, Empagliflozin (EMPA), suppresses cardiomyocytes autosis (autophagic cell death) to confer...

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Detalles Bibliográficos
Autores principales:	Jiang, Kai, Xu, Yue, Wang, Dandan, Chen, Feng, Tu, Zizhuo, Qian, Jie, Xu, Sheng, Xu, Yixiang, Hwa, John, Li, Jian, Shang, Hongcai, Xiang, Yaozu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008115/ https://www.ncbi.nlm.nih.gov/pubmed/33417139 http://dx.doi.org/10.1007/s13238-020-00809-4

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