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Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome

Recent studies suggest that blood flow changes in the median nerve may help confirm a diagnosis of carpal tunnel syndrome (CTS). Herein, we examined the utility of superb microvascular imaging (SMI), a new ultrasonographic (US) technique for visualizing microvascular flow, for detecting blood flow d...

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Autores principales: Endo, Takeshi, Matsui, Yuichiro, Kawamura, Daisuke, Urita, Atsushi, Momma, Daisuke, Ota, Mitsutoshi, Shibayama, Hiroki, Iwai, Takahito, Nishida, Mutsumi, Iwasaki, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008197/
https://www.ncbi.nlm.nih.gov/pubmed/35432160
http://dx.doi.org/10.3389/fneur.2022.832569
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author Endo, Takeshi
Matsui, Yuichiro
Kawamura, Daisuke
Urita, Atsushi
Momma, Daisuke
Ota, Mitsutoshi
Shibayama, Hiroki
Iwai, Takahito
Nishida, Mutsumi
Iwasaki, Norimasa
author_facet Endo, Takeshi
Matsui, Yuichiro
Kawamura, Daisuke
Urita, Atsushi
Momma, Daisuke
Ota, Mitsutoshi
Shibayama, Hiroki
Iwai, Takahito
Nishida, Mutsumi
Iwasaki, Norimasa
author_sort Endo, Takeshi
collection PubMed
description Recent studies suggest that blood flow changes in the median nerve may help confirm a diagnosis of carpal tunnel syndrome (CTS). Herein, we examined the utility of superb microvascular imaging (SMI), a new ultrasonographic (US) technique for visualizing microvascular flow, for detecting blood flow differences between CTS patients and healthy controls. We performed a retrospective analysis of 28 hands with suspected CTS. Patients received both nerve conduction and US examinations. Ten healthy volunteers were enrolled as the control group. The nerve compression ratio and the blood flow signal area were quantified using color Doppler US (CDUS), power Doppler US (PDUS), and SMI. Correlation analyses between the blood flow signal area, the compound muscle action potential of the thenar muscle, and the nerve compression ratio were performed. As a result, the mean nerve compression ratio was found to be significantly higher in the CTS group. There were no differences in the blood flow signal area between the groups using CDUS, while PDUS and SMI showed higher blood flow signals in the CTS group. The blood flow signal area measured by SMI had stronger correlations with the compound muscle action potential amplitude and the nerve compression ratio than those for PDUS. The diagnostic utility of SMI was equivalent to PDUS, but superior to conventional CDUS. Nevertheless, the blood flow signal by SMI was more strongly correlated with the electrophysiological severity and compression ratio than for PDUS. Use of SMI in future studies may help clarify the underlying mechanisms of blood flow changes in CTS.
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spelling pubmed-90081972022-04-15 Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome Endo, Takeshi Matsui, Yuichiro Kawamura, Daisuke Urita, Atsushi Momma, Daisuke Ota, Mitsutoshi Shibayama, Hiroki Iwai, Takahito Nishida, Mutsumi Iwasaki, Norimasa Front Neurol Neurology Recent studies suggest that blood flow changes in the median nerve may help confirm a diagnosis of carpal tunnel syndrome (CTS). Herein, we examined the utility of superb microvascular imaging (SMI), a new ultrasonographic (US) technique for visualizing microvascular flow, for detecting blood flow differences between CTS patients and healthy controls. We performed a retrospective analysis of 28 hands with suspected CTS. Patients received both nerve conduction and US examinations. Ten healthy volunteers were enrolled as the control group. The nerve compression ratio and the blood flow signal area were quantified using color Doppler US (CDUS), power Doppler US (PDUS), and SMI. Correlation analyses between the blood flow signal area, the compound muscle action potential of the thenar muscle, and the nerve compression ratio were performed. As a result, the mean nerve compression ratio was found to be significantly higher in the CTS group. There were no differences in the blood flow signal area between the groups using CDUS, while PDUS and SMI showed higher blood flow signals in the CTS group. The blood flow signal area measured by SMI had stronger correlations with the compound muscle action potential amplitude and the nerve compression ratio than those for PDUS. The diagnostic utility of SMI was equivalent to PDUS, but superior to conventional CDUS. Nevertheless, the blood flow signal by SMI was more strongly correlated with the electrophysiological severity and compression ratio than for PDUS. Use of SMI in future studies may help clarify the underlying mechanisms of blood flow changes in CTS. Frontiers Media S.A. 2022-03-31 /pmc/articles/PMC9008197/ /pubmed/35432160 http://dx.doi.org/10.3389/fneur.2022.832569 Text en Copyright © 2022 Endo, Matsui, Kawamura, Urita, Momma, Ota, Shibayama, Iwai, Nishida and Iwasaki. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Endo, Takeshi
Matsui, Yuichiro
Kawamura, Daisuke
Urita, Atsushi
Momma, Daisuke
Ota, Mitsutoshi
Shibayama, Hiroki
Iwai, Takahito
Nishida, Mutsumi
Iwasaki, Norimasa
Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome
title Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome
title_full Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome
title_fullStr Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome
title_full_unstemmed Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome
title_short Diagnostic Utility of Superb Microvascular Imaging and Power Doppler Ultrasonography for Visualizing Enriched Microvascular Flow in Patients With Carpal Tunnel Syndrome
title_sort diagnostic utility of superb microvascular imaging and power doppler ultrasonography for visualizing enriched microvascular flow in patients with carpal tunnel syndrome
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008197/
https://www.ncbi.nlm.nih.gov/pubmed/35432160
http://dx.doi.org/10.3389/fneur.2022.832569
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