PPARγ Ameliorates Mycobacterium tuberculosis H37Ra-Induced Foamy Macrophage Formation via the ABCG1-Dependent Cholesterol Efflux Pathway in THP-1 Macrophages

Foamy macrophages are present during the course of Mycobacterium tuberculosis (Mtb) infection and seems to be nutrient-rich reservoir and secure reservoir for the bacilli, which leads to bacterial persistence and infection transmission. Peroxisome proliferator activated receptor γ (PPARγ) is a key t...

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Detalles Bibliográficos
Autores principales: Ye, Yutao, Liu, Jun, Guo, Yang, Gao, Yujie, Rao, Jiayue, Su, Rigu, Zhang, Lu, Huang, Zikun, Luo, Qing, Li, Junming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008364/
https://www.ncbi.nlm.nih.gov/pubmed/35432274
http://dx.doi.org/10.3389/fmicb.2022.829870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008364/
https://www.ncbi.nlm.nih.gov/pubmed/35432274
http://dx.doi.org/10.3389/fmicb.2022.829870

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