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Native Ambient Mass Spectrometry Enables Analysis of Intact Endogenous Protein Assemblies up to 145 kDa Directly from Tissue

[Image: see text] Untargeted label-free interrogation of proteins in their functional form directly from their physiological environment promises to transform life sciences research by providing unprecedented insight into their transient interactions with other biomolecules and xenobiotics. Native a...

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Detalles Bibliográficos
Autores principales: Hale, Oliver J., Hughes, James W., Sisley, Emma K., Cooper, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008691/
https://www.ncbi.nlm.nih.gov/pubmed/35358391
http://dx.doi.org/10.1021/acs.analchem.1c05353