Applications of Non-Coding RNAs in Patients With Retinoblastoma

Retinoblastoma (RB) is the most common primary intraocular malignancy in childhood. In the carcinogenic process of neoplasms such as RB, the role of non-coding RNAs (ncRNAs) has been widely demonstrated recently. In this review, we aim to provide a clinical overview of the current knowledge regardin...

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Autores principales: Fernandez-Diaz, Daniel, Rodriguez-Vidal, Cristina, Silva-Rodríguez, Paula, Paniagua, Laura, Blanco-Teijeiro, María José, Pardo, María, Piñeiro, Antonio, Bande, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008704/
https://www.ncbi.nlm.nih.gov/pubmed/35432447
http://dx.doi.org/10.3389/fgene.2022.842509
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author Fernandez-Diaz, Daniel
Rodriguez-Vidal, Cristina
Silva-Rodríguez, Paula
Paniagua, Laura
Blanco-Teijeiro, María José
Pardo, María
Piñeiro, Antonio
Bande, Manuel
author_facet Fernandez-Diaz, Daniel
Rodriguez-Vidal, Cristina
Silva-Rodríguez, Paula
Paniagua, Laura
Blanco-Teijeiro, María José
Pardo, María
Piñeiro, Antonio
Bande, Manuel
author_sort Fernandez-Diaz, Daniel
collection PubMed
description Retinoblastoma (RB) is the most common primary intraocular malignancy in childhood. In the carcinogenic process of neoplasms such as RB, the role of non-coding RNAs (ncRNAs) has been widely demonstrated recently. In this review, we aim to provide a clinical overview of the current knowledge regarding ncRNAs in relation to RB. Although ncRNAs are now considered as potential diagnostic biomarkers, prognostic factors, and therapeutic targets, further studies will facilitate enhanced understanding of ncRNAs in RB physiopathology and define the roles ncRNAs can play in clinical practice.
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spelling pubmed-90087042022-04-15 Applications of Non-Coding RNAs in Patients With Retinoblastoma Fernandez-Diaz, Daniel Rodriguez-Vidal, Cristina Silva-Rodríguez, Paula Paniagua, Laura Blanco-Teijeiro, María José Pardo, María Piñeiro, Antonio Bande, Manuel Front Genet Genetics Retinoblastoma (RB) is the most common primary intraocular malignancy in childhood. In the carcinogenic process of neoplasms such as RB, the role of non-coding RNAs (ncRNAs) has been widely demonstrated recently. In this review, we aim to provide a clinical overview of the current knowledge regarding ncRNAs in relation to RB. Although ncRNAs are now considered as potential diagnostic biomarkers, prognostic factors, and therapeutic targets, further studies will facilitate enhanced understanding of ncRNAs in RB physiopathology and define the roles ncRNAs can play in clinical practice. Frontiers Media S.A. 2022-03-31 /pmc/articles/PMC9008704/ /pubmed/35432447 http://dx.doi.org/10.3389/fgene.2022.842509 Text en Copyright © 2022 Fernandez-Diaz, Rodriguez-Vidal, Silva-Rodríguez, Paniagua, Blanco-Teijeiro, Pardo, Piñeiro and Bande. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Fernandez-Diaz, Daniel
Rodriguez-Vidal, Cristina
Silva-Rodríguez, Paula
Paniagua, Laura
Blanco-Teijeiro, María José
Pardo, María
Piñeiro, Antonio
Bande, Manuel
Applications of Non-Coding RNAs in Patients With Retinoblastoma
title Applications of Non-Coding RNAs in Patients With Retinoblastoma
title_full Applications of Non-Coding RNAs in Patients With Retinoblastoma
title_fullStr Applications of Non-Coding RNAs in Patients With Retinoblastoma
title_full_unstemmed Applications of Non-Coding RNAs in Patients With Retinoblastoma
title_short Applications of Non-Coding RNAs in Patients With Retinoblastoma
title_sort applications of non-coding rnas in patients with retinoblastoma
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008704/
https://www.ncbi.nlm.nih.gov/pubmed/35432447
http://dx.doi.org/10.3389/fgene.2022.842509
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