Combined Subcutaneous-Intranasal Immunization With Epitope-Based Antigens Elicits Binding and Neutralizing Antibody Responses in Serum and Mucosae Against PRRSV-2 and SARS-CoV-2

New vaccine design approaches, platforms, and immunization strategies might foster antiviral mucosal effector and memory responses to reduce asymptomatic infection and transmission in vaccinated individuals. Here, we investigated a combined parenteral and mucosal immunization scheme to induce local...

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Detalles Bibliográficos
Autores principales: Fragoso-Saavedra, Mario, Ramírez-Estudillo, Carmen, Peláez-González, Diana L., Ramos-Flores, Jorge O., Torres-Franco, Gustavo, Núñez-Muñoz, Leandro, Marcelino-Pérez, Gabriel, Segura-Covarrubias, María G., González-González, Rogelio, Ruiz-Medrano, Roberto, Xoconostle-Cázares, Beatriz, Gayosso-Vázquez, Amanda, Reyes-Maya, Silvia, Ramírez-Andoney, Vianey, Alonso-Morales, Rogelio A., Vega-López, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008747/
https://www.ncbi.nlm.nih.gov/pubmed/35432364
http://dx.doi.org/10.3389/fimmu.2022.848054

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